Gene

alcama

ID
ZDB-GENE-990415-30
Name
activated leukocyte cell adhesion molecule a
Symbol
alcama Nomenclature History
Previous Names
  • alcam (1)
  • cd166 (1)
  • DM-GRASP (1)
  • neurolin-a (1)
  • neurolin (1)
  • zn5 / zn-5 antigen (1)
  • zn8 / zn-8 antigen
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Enables identical protein binding activity. Involved in cartilage morphogenesis; positive regulation of cell morphogenesis involved in differentiation; and positive regulation of gene expression. Acts upstream of or within animal organ development and axonogenesis. Located in axon. Is expressed in several structures, including digestive system; immature eye; musculature system; nervous system; and pericardial region. Orthologous to human ALCAM (activated leukocyte cell adhesion molecule).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
171 figures from 99 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
14 figures from 5 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With alcama Human Ortholog
No data available
Associated With alcama Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR003006 Immunoglobulin/major histocompatibility complex, conserved site
Domain IPR003598 Immunoglobulin subtype 2
Domain IPR003599 Immunoglobulin subtype
Domain IPR007110 Immunoglobulin-like domain
Domain IPR013106 Immunoglobulin V-set domain
Domain IPR013162 CD80-like, immunoglobulin C2-set
Family IPR039810 CD166 antigen
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
Domain Details Per Protein
Protein Length CD166 antigen CD80-like, immunoglobulin C2-set Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold Immunoglobulin/major histocompatibility complex, conserved site Immunoglobulin subtype Immunoglobulin subtype 2 Immunoglobulin V-set domain
UniProtKB:Q6IQX4 564
UniProtKB:Q90460 564
UniProtKB:A0A2R8RU51 564
UniProtKB:Q7ZZ85 381
UniProtKB:A0A2R8PVV3 562
UniProtKB:F1QD88 545
UniProtKB:A4JYG4 497
UniProtKB:A0A2R8PV55 555
UniProtKB:Q7ZU00 564
UniProtKB:Q8AW46 20
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab2-alcama polyclonal Rabbit
  • IHC
4
zn-5 monoclonal IgG1 , k Mouse
  • IHC
  • WB
Zebrafish International Resource Center (ZIRC)  (order this)
216
Ab3-alcama monoclonal Mouse
  • IHC
3
Ab1-alcama monoclonal IgG Mouse
  • WB
2
zn-8 monoclonal IgG1 , k Mouse
  • IHC
Developmental Studies Hybridoma Bank
Zebrafish International Resource Center (ZIRC)  (order this)
172
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations