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Phenotype Figure Summary
Marker:
alcama
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
El-Brolosy
et al.
, 2019
Fig. 1
alcama
bns201/bns201
whole organism
alcama
expression decreased amount, abnormal
Fig. 3
alcama
bns244/bns244
whole organism
alcama
expression absent, abnormal
Fig. S6
alcama
bns244/bns244
cardiac ventricle elongated, abnormal
Choe
et al.
, 2013
Fig. 5
WT + MO1-alcama
pharyngeal pouch adherens junction organization process quality, abnormal
pharyngeal pouch apical protein localization decreased occurrence, abnormal
pharyngeal pouch malformed, abnormal
Choudhry
et al.
, 2013
Fig. 7
WT + MO3-alcama
heart looping disrupted, abnormal
Choudhry
et al.
, 2011
Fig. 1
WT + MO4-alcama
Meckel's cartilage bent, abnormal
Meckel's cartilage protruding, abnormal
pericardium edematous, abnormal
splanchnocranium decreased length, abnormal
swim bladder absent, abnormal
ventral mandibular arch decreased length, abnormal
Fig. 2
WT + MO4-alcama
ceratohyal cartilage fused with hyosymplectic cartilage, abnormal
interhyal cartilage absent, abnormal
Meckel's cartilage bent, abnormal
Meckel's cartilage fused with palatoquadrate cartilage, abnormal
Diekmann
et al.
, 2009
Fig. 3
WT + MO1-alcama + MO1-tp53
eye decreased size, abnormal
eye mislocalised ventrally, abnormal
pericardial cavity increased size, abnormal
ventral mandibular arch decreased size, abnormal
whole organism decreased size, abnormal
Fig. 4
WT + MO1-alcama + MO1-tp53
eye decreased diameter, abnormal
eye decreased size, abnormal
optic nerve head axon absent, abnormal
optic nerve head decreased size, abnormal
retinal ganglion cell decreased amount, abnormal
retinal ganglion cell layer morphology, abnormal
retinal inner nuclear layer neuron decreased amount, abnormal
retinal neural layer nucleus apoptotic, abnormal
Fig. 5
WT + MO1-alcama + MO1-tp53
cranial nerve II aplastic, abnormal
cranial nerve II decreased thickness, abnormal
Fig. 6
WT + MO1-alcama + MO1-tp53
neuron differentiation arrested, abnormal
neuron differentiation decreased rate, abnormal
retina morphogenesis in camera-type eye disrupted, abnormal
retinal ganglion cell decreased amount, abnormal
Fig. 7
s356tTg + MO1-alcama + MO1-tp53
amacrine cell decreased amount, abnormal
cranial nerve II aplastic, abnormal
cranial nerve II decreased thickness, abnormal
neuron differentiation arrested, abnormal
retina morphogenesis in camera-type eye disrupted, abnormal
retinal ganglion cell decreased amount, abnormal
retinal rod cell differentiation delayed, abnormal
retinal rod cell differentiation process quality, abnormal
Fig. S2
WT + MO1-alcama
, 
WT + MO1-alcama + MO1-tp53
eye decreased size, abnormal
text only
WT + MO2-alcama
eye decreased size, abnormal
eye mislocalised ventrally, abnormal
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