Gene

ptp4a1

ID

ZDB-GENE-041121-11

Name

protein tyrosine phosphatase 4A1

Symbol

ptp4a1 Nomenclature History

Previous Names

PRL-1 (1)
fb54d08
fc01c04
wu:fb54d08
wu:fc01c04
zgc:101726

Type

protein_coding_gene

Location

Chr: 11 Mapping Details/Browsers

Description

Predicted to enable protein tyrosine phosphatase activity. Predicted to act upstream of or within protein dephosphorylation. Predicted to be located in endosome and plasma membrane. Predicted to be active in cytoplasm and nucleus. Is expressed in gut; myotome; nervous system; and pharyngeal arch. Orthologous to human PTP4A1 (protein tyrosine phosphatase 4A1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:101726 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ptp4a1 Human Ortholog

No data available

Associated With ptp4a1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000387	Tyrosine-specific protein phosphatases domain
Domain	IPR003595	Protein-tyrosine phosphatase, catalytic
Domain	IPR020422	Dual specificity protein phosphatase domain
Family	IPR050561	Protein Tyrosine Phosphatase
Homologous_superfamily	IPR029021	Protein-tyrosine phosphatase-like

Domain Details Per Protein

Protein	Additional Resources	Length	Dual specificity protein phosphatase domain	Protein Tyrosine Phosphatase	Protein-tyrosine phosphatase, catalytic	Protein-tyrosine phosphatase-like	Tyrosine-specific protein phosphatases domain
UniProtKB:F1QSC9	InterPro	173
UniProtKB:A0A0R4IN05	InterPro	184

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
aberrant processed transcript	ptp4a1-205 (1) Ensembl	Ensembl	806 nt	Select Tool ZFIN BLAST
aberrant processed transcript	ptp4a1-206 (1) Ensembl	Ensembl	1,109 nt	Select Tool ZFIN BLAST
mRNA	ptp4a1-201 (1) Ensembl	Ensembl	2,002 nt	Select Tool ZFIN BLAST
mRNA	ptp4a1-202 (1) Ensembl	Ensembl	727 nt	Select Tool ZFIN BLAST
mRNA	ptp4a1-203 (1) Ensembl	Ensembl	1,411 nt	Select Tool ZFIN BLAST
mRNA	ptp4a1-204 (1) Ensembl	Ensembl	135 nt	Select Tool ZFIN BLAST
mRNA	ptp4a1-208 (1) Ensembl	Ensembl	821 nt	Select Tool ZFIN BLAST
mRNA	ptp4a1-209 (1) Ensembl	Ensembl	541 nt	Select Tool ZFIN BLAST
ncRNA	ptp4a1-007 (1) Ensembl	Ensembl	942 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations