ZFIN is now using GRCz12tu for Genomic Data
Gene
gbp1
- ID
- ZDB-GENE-040718-32
- Name
- guanylate binding protein 1
- Symbol
- gbp1 Nomenclature History
- Previous Names
-
- wu:fd36d06
- zgc:92185 (1)
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable GTP binding activity and GTPase activity. Is expressed in thyroid follicle. Orthologous to several human genes including GBP6 (guanylate binding protein family member 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Yang et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003191 | Guanylate-binding protein/Atlastin, C-terminal |
| Domain | IPR015894 | Guanylate-binding protein, N-terminal |
| Domain | IPR030386 | GB1/RHD3-type guanine nucleotide-binding (G) domain |
| Domain | IPR037684 | Guanylate-binding protein, C-terminal |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036543 | Guanylate-binding protein, C-terminal domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | GB1/RHD3-type guanine nucleotide-binding (G) domain | Guanylate-binding protein/Atlastin, C-terminal | Guanylate-binding protein, C-terminal | Guanylate-binding protein, C-terminal domain superfamily | Guanylate-binding protein, N-terminal | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q6DHP7 | InterPro | 621 | ||||||
| UniProtKB:A0ACD6B589 | InterPro | 622 | ||||||
| UniProtKB:A0AC58GPP6 | InterPro | 622 | ||||||
| UniProtKB:A0AC58GPQ2 | InterPro | 622 |
- Genome Browsers
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-gbp1 | polyclonal | IgG | Rabbit |
|
Sigma-Aldrich
|
2 |
Plasmids
No data available
- Genome Browsers