Gene
nek2
- ID
- ZDB-GENE-040426-752
- Name
- NIMA-related kinase 2
- Symbol
- nek2 Nomenclature History
- Previous Names
-
- zgc:55602
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have protein serine/threonine kinase activity. Involved in retinal rod cell development. Predicted to localize to centrosome; cytoplasm; and nucleus. Human ortholog(s) of this gene implicated in retinitis pigmentosa 67. Orthologous to human NEK2 (NIMA related kinase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55602 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Nishiguchi et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| retinitis pigmentosa 67 | Alliance | ?Retinitis pigmentosa 67 | 615565 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | NEK Ser/Thr protein kinase family, NIMA subfamily | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|
|
UniProtKB:Q7ZUN2
|
440 |
Interactions and Pathways
No data available
Plasmids
No data available