Gene

junbb

ID

ZDB-GENE-040426-2666

Name

JunB proto-oncogene, AP-1 transcription factor subunit b

Symbol

junbb Nomenclature History

Previous Names

junbl
wu:fa95h09
wu:fj44e11
wu:fj68b07
zgc:63933

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within fin regeneration and lymph vessel development. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Is expressed in several structures, including Kupffer's vesicle; fin; nervous system; optic vesicle; and pectoral fin bud. Human ortholog(s) of this gene implicated in head and neck squamous cell carcinoma and melanoma. Orthologous to human JUNB (JunB proto-oncogene, AP-1 transcription factor subunit).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

29 figures from 19 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:63933 (9 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from Kiesow et al., 2015
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With junbb Human Ortholog

No data available

Associated With junbb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR004827	Basic-leucine zipper domain
Domain	IPR005643	Jun-like transcription factor
Family	IPR002112	Transcription factor Jun
Family	IPR050946	AP-1 Transcription Factor bZIP
Homologous_superfamily	IPR008917	Transcription factor, Skn-1-like, DNA-binding domain superfamily
Homologous_superfamily	IPR046347	Basic-leucine zipper domain superfamily