ZFIN ID: ZDB-GENE-040303-1
Gene Name: DAB adaptor protein 2
Gene Symbol: dab2    Nomenclature History

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Previous Name: sb:cb778

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Involved in several processes, including angiogenesis; regulation of cardiac muscle cell differentiation; and regulation of signal transduction. Predicted to localize to cytoplasm and plasma membrane. Is expressed in several structures, including intermediate cell mass of mesoderm; intestinal bulb; pronephros; vasculature; and ventral mesoderm. Orthologous to human DAB2 (DAB adaptor protein 2).
Genome Resources: Alliance (1),  Gene:404040 (1),  Ensembl(GRCz11):ENSDARG00000031761 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
pd1162 Small Deletion Unknown Unknown
sa45210 Point Mutation Unknown Missense, Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-dab2
    1
    CRISPR2-dab2 1
    MO1-dab2 N/A 3
    DISEASE ASSOCIATED WITH dab2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH dab2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process Notch signaling pathway (more)
    Cellular Component cytoplasm (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA dab2-201 (1)    Ensembl 2444
    dab2-203 (1)    Ensembl 1723
    dab2-204 (1)    Ensembl 2336
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dab2
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    tgbac(dab2:egfp) dab2 EGFP Danio rerio 1 1
    MARKER RELATIONSHIPS
    dab2 Contained in: [BAC] CH211-158M24 (1)
    dab2 Encodes: [EST] cb778 (1) (order this), eu105 (1)
    [cDNA] MGC:77136 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_205757 (1) 2302 nt
    Genomic GenBank:BX510649 (1) 189844 nt
    Select Tool
    Polypeptide UniProtKB:B8A566 (1) 797 aa
    Sequence Information (all 26)
    ORTHOLOGY for dab2 ( Chr: 5 )
    CITATIONS (82)