Gene
dab2
- ID
- ZDB-GENE-040303-1
- Name
- DAB adaptor protein 2
- Symbol
- dab2 Nomenclature History
- Previous Names
-
- sb:cb778
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable cargo receptor activity and clathrin adaptor activity. Acts upstream of or within several processes, including Notch signaling pathway; regulation of cardiac muscle cell differentiation; and regulation of signal transduction. Predicted to be active in clathrin-coated pit; cytoplasm; and intracellular membrane-bounded organelle. Is expressed in several structures, including intermediate cell mass of mesoderm; pleuroperitoneal region; vascular cord; vasculature; and ventral mesoderm. Orthologous to human DAB2 (DAB adaptor protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 50 figures from 35 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb778 (14 images)
- eu105 (12 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Disabled homolog 1/2, sulfatide-binding motif | Disabled, phosphotyrosine-binding domain | PH-like domain superfamily | PTB/PI domain |
|---|---|---|---|---|---|---|
| UniProtKB:A0A8M1P9G4 | InterPro | 797 | ||||
| UniProtKB:F6NGQ6 | InterPro | 589 |
- Genome Browsers
Interactions and Pathways
Plasmids
No data available