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ZIRC
ZFIN ID: ZDB-GENE-031118-121
Gene Name: erb-b2 receptor tyrosine kinase 2
Gene Symbol: erbb2
Sequence Ontology ID : SO:0000704

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Previous Names: wu:fv70f10, zgc:63601

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(Including Attributions)
Location: Chr: 12 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have transmembrane receptor protein tyrosine kinase activity; involved in several processes, including animal organ development, fin regeneration, and nervous system development;  ...
GENE EXPRESSION
All Expression Data: 4 figures from 4 publications
Wild-type Stages, Structures: Segmentation:5-9 somites (11.66h-14.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la012096Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la012097Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la012098Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la018007Tg Transgenic Insertion Unknown Unknown DNA
    nksagff202aTg Transgenic Insertion Unknown Unknown DNA
    sa18607 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa27894 Point Mutation Unknown Premature Stop ENU
    sa35218 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • st50 Point Mutation Unknown Missense
    st61 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • t20604 Unknown Unknown Unknown
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH erbb2 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    lung cancer Adenocarcinoma of lung, somatic 211980
    stomach cancer Gastric cancer, somatic 613659
    Ovarian cancer, somatic,
    Glioblastoma, somatic 137800
    DISEASE ASSOCIATED WITH erbb2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process axonal fasciculation (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ATP binding (more)
    GO Terms (all 26)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA erbb2-002 (1) 765
    mRNA erbb2-201 (1) 4093
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM erbb2 No data available
    MARKER RELATIONSHIPS
    erbb2Contained in: [BAC] DKEY-25P11 (1) (order this)
    erbb2Has Artifact: [cDNA] WITHDRAWN:MGC:63601 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200119 (1) 3956bp
    Genomic GenBank:CR457459 (1) 206901bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1R5S1 (1) 1275aa
    Sequence Clusters UniGene:52559 (1)
    Sequence Information (all 12)
    ORTHOLOGY for erbb2 (Chr: 12)
    CITATIONS (64)