ZFIN ID: ZDB-GENE-030516-3
Gene Name: collagen type XVIII alpha 1 chain a
Gene Symbol: col18a1a    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: cb371 (1), col18a1, cb529 (1), fc96d06, sb:cb529 (1), wu:fb47h10, wu:fb77g12, wu:fc50f04, wu:fc96d06, wu:fk02h12

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have extracellular matrix structural constituent. Involved in neural crest cell migration. Predicted to localize to the extracellular matrix and extracellular space. Is expressed in several structures, including anterior neural keel; digestive system; nervous system; neural plate; and pronephros. Orthologous to human COL18A1 (collagen type XVIII alpha 1 chain).
Genome Resources: Alliance (1),  Gene:564123 (1),  Ensembl(GRCz11):ENSDARG00000036558 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la026994Tg Transgenic Insertion Unknown Unknown DNA
la026995Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la026996Tg Transgenic Insertion Unknown Unknown DNA
    la029609Tg Transgenic Insertion Unknown Unknown DNA
    la029610Tg Transgenic Insertion Unknown Unknown DNA
    sa34722 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-col18a1a N/A 2
    MO2-col18a1a N/A 1
    PHENOTYPE
    Data: Fig. 4 from Banerjee et al., 2013
    Observed in:
    DISEASE ASSOCIATED WITH col18a1a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Knobloch syndrome, type 1 267750
    DISEASE ASSOCIATED WITH col18a1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process neural crest cell migration (more)
    Cellular Component collagen trimer (more)
    Molecular Function extracellular matrix structural constituent (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR001791 Laminin G domain
    Repeat IPR008160 Collagen triple helix repeat
    Domain IPR010515 Collagenase NC10/endostatin
    Homologous_superfamily IPR013320 Concanavalin A-like lectin/glucanase domain superfamily
    Homologous_superfamily IPR016186 C-type lectin-like/link domain superfamily
    Homologous_superfamily IPR016187 C-type lectin fold
    Domain IPR020067 Frizzled domain
    Domain IPR035523 Collagen alpha-1(XVIII) chain, frizzled domain
    Homologous_superfamily IPR036790 Frizzled cysteine-rich domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA col18a1a-201 (1)    Ensembl 5579
    col18a1a-202 (1)    Ensembl 5515
    col18a1a-203 (1)    Ensembl 6365
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM col18a1a No data available
    MARKER RELATIONSHIPS
    col18a1a Contained in: [BAC] DKEY-237E16 (1) (order this), DKEYP-30E7 (1)
    col18a1a Encodes: [EST] cb371 (1) (order this), cb529 (2) (order this), fb47h10 (1), fb77g12 (1), fc50f04 (1) (order this), fc96d06, fk02h12
    [cDNA] MGC:195107 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001039630 (1) 4191 bp
    Genomic GenBank:BX927363 (1) 134994 bp
    Select Tool
    Polypeptide UniProtKB:B0S8G4 (1) 1645 aa
    Sequence Information (all 48)
    ORTHOLOGY for col18a1a ( Chr: 9 )
    CITATIONS (38)