Gene
aff3
- ID
- ZDB-GENE-030219-193
- Name
- AF4/FMR2 family, member 3
- Symbol
- aff3 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to be involved in regulation of gene expression. Predicted to be located in nucleus. Predicted to be part of super elongation complex. Is expressed in notochord. Human ortholog(s) of this gene implicated in KINSSHIP syndrome. Orthologous to human AFF3 (ALF transcription elongation factor 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Bassani et al., 2024
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| KINSSHIP syndrome | Alliance | KINSSHIP syndrome | 619297 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | AF4/FMR2, C-terminal homology domain | AF4/FMR2 family |
|---|---|---|---|
|
UniProtKB:A0A8M3AW05
|
1242 |
Interactions and Pathways
No data available
Plasmids
No data available