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ZIRC
ZFIN ID: ZDB-GENE-030131-9076
Gene Name: annexin A5b
Gene Symbol: anxa5b    Nomenclature History

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Previous Names: anx, anxa5, cb989 (1), wu:fa98f06, wu:fj10f10 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have calcium ion binding activity and calcium-dependent phospholipid binding activity. Involved in regulation of cell motility. Localizes to the cytoplasm. Human ortholog(s) of this gene implicated in autoimmune disease of the nervous system; myocardial infarction; and systemic scleroderma. Is expressed in olfactory placode; peripheral olfactory organ; swim bladder; swim bladder bud; and visceral peritoneum. Orthologous to human ANXA5 (annexin A5).
Genome Resources: Alliance (1),  Gene:337132 (1),  Ensembl(GRCz11):ENSDARG00000016470 (2)
Note:
GENE EXPRESSION
All Expression Data: 13 figures from 8 publications
Directly Submitted Expression Data: 4 figures (8 images) from Thisse et al., 2001 [cb989]
Wild-type Stages, Structures: Cleavage:16-cell (1.5h-1.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la021046Tg Transgenic Insertion Unknown Unknown DNA
y312Et Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zko429a Indel Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • zko429b Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-anxa5b 1
    MO1-anxa5b N/A 1
    MO2-anxa5b N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH anxa5b HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    {Pregnancy loss, recurrent, susceptibility to, 3} 614391
    DISEASE ASSOCIATED WITH anxa5b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of cell motility (more)
    Cellular Component cytoplasm (more)
    Molecular Function calcium-dependent phospholipid binding (more)
    GO Terms (all 5)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA anxa5b-201 (1)    Ensembl 1881
    anxa5b-202 (1)    Ensembl 963
    Browsers: UCSCEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM anxa5b No data available
    MARKER RELATIONSHIPS
    anxa5b Contained in: [Fosmid] ZFOS-2069A7 (1)
    anxa5b Contains: [SNP] rs3727535 (1), rs3727536 (1)
    anxa5b Encodes: [EST] cb989 (1) (order this), fa98f06, fj10f10 (1)
    [cDNA] MGC:55312 (1) (order this), MGC:77626 (1) (order this), MGC:174837 (1) (order this), MGC:191287 (1) (order this)
    anxa5b Has Artifact: [EST] fb07f04
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_181757 (1) 1930 bp
    Genomic GenBank:FP102886 (1) 38415 bp
    Select Tool
    Polypeptide UniProtKB:A9JTC0 (1) 317 aa
    Sequence Clusters UniGene:75805 (1)
    Sequence Information (all 33)
    ORTHOLOGY for anxa5b ( Chr: 1 )
    CITATIONS (47)