Gene

aldh1a2

ID
ZDB-GENE-011010-3
Name
aldehyde dehydrogenase 1 family, member A2
Symbol
aldh1a2 Nomenclature History
Previous Names
  • raldh2 (1)
  • neckless
  • nls
  • no-fin (1)
  • nof (1)
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have aldehyde dehydrogenase (NAD+) activity. Involved in several processes, including animal organ development; face morphogenesis; and myelination. Is expressed in several structures, including head; heart; immature eye; mesoderm; and pleuroperitoneal region. Orthologous to human ALDH1A2 (aldehyde dehydrogenase 1 family member A2).
Genome Resources
Note
None
Expression
All Expression Data
121 figures from 91 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
39 figures from 23 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With aldh1a2 Human Ortholog
No data available
Associated With aldh1a2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR016160 Aldehyde dehydrogenase, cysteine active site
Conserved_site IPR029510 Aldehyde dehydrogenase, glutamic acid active site
Domain IPR015590 Aldehyde dehydrogenase domain
Homologous_superfamily IPR016161 Aldehyde/histidinol dehydrogenase
Homologous_superfamily IPR016162 Aldehyde dehydrogenase, N-terminal
Homologous_superfamily IPR016163 Aldehyde dehydrogenase, C-terminal
Domain Details Per Protein
Protein Length Aldehyde dehydrogenase, C-terminal Aldehyde dehydrogenase, cysteine active site Aldehyde dehydrogenase domain Aldehyde dehydrogenase, glutamic acid active site Aldehyde dehydrogenase, N-terminal Aldehyde/histidinol dehydrogenase
UniProtKB:Q90Y03 518
UniProtKB:Q90XS8 518
UniProtKB:B3DKM0 518
UniProtKB:Q8QGQ1 518
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-aldh1a2 polyclonal IgG Rabbit
  • IHC
GeneTex
11
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations