Gene

supt5h

ID
ZDB-GENE-001207-1
Name
SPT5 homolog, DSIF elongation factor subunit
Symbol
supt5h Nomenclature History
Previous Names
  • Spt5
  • etID10129.15 (1)
  • etID37101.15 (1)
  • fb37g01
  • fb95e05
  • fog
  • foggy
  • wu:fb37g01 (1)
  • wu:fb95e05 (1)
  • wu:fc10f02
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Exhibits DNA binding activity. Involved in several processes, including generation of neurons; regulation of signal transduction; and regulation of transcription elongation from RNA polymerase II promoter. Localizes to nucleus. Is expressed in brain and optic cup. Orthologous to human SUPT5H (SPT5 homolog, DSIF elongation factor subunit).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
16 figures from 8 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With supt5h Human Ortholog
No data available
Associated With supt5h Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR005100 NGN domain
Domain IPR005824 KOW
Domain IPR006645 NusG-like, N-terminal
Domain IPR022581 Spt5 transcription elongation factor, N-terminal
Domain IPR024945 Spt5 C-terminal domain
Domain IPR039385 NGN domain, eukaryotic
Domain IPR041973 Spt5, KOW domain repeat 1
Domain IPR041975 Spt5, KOW domain repeat 2
Domain IPR041976 Spt5, KOW domain repeat 3
Domain IPR041977 Spt5, KOW domain repeat 4
Domain IPR041978 Spt5, KOW domain repeat 5
Domain IPR041980 Spt5, KOW domain repeat 6
Family IPR017071 Transcription elongation factor Spt5, eukaryote
Family IPR039659 Transcription elongation factor SPT5
Homologous_superfamily IPR008991 Translation protein SH3-like domain superfamily
Homologous_superfamily IPR014722 Large ribosomal subunit protein uL2, domain 2
Homologous_superfamily IPR036735 NusG, N-terminal domain superfamily
Domain Details Per Protein
Protein Length KOW Large ribosomal subunit protein uL2, domain 2 NGN domain NGN domain, eukaryotic NusG-like, N-terminal NusG, N-terminal domain superfamily Spt5 C-terminal domain Spt5, KOW domain repeat 1 Spt5, KOW domain repeat 2 Spt5, KOW domain repeat 3 Spt5, KOW domain repeat 4 Spt5, KOW domain repeat 5 Spt5, KOW domain repeat 6 Spt5 transcription elongation factor, N-terminal Transcription elongation factor SPT5 Transcription elongation factor Spt5, eukaryote Translation protein SH3-like domain superfamily
UniProtKB:Q9DDT5
InterPro
1084
UniProtKB:A0A8M9Q0J3
InterPro
1086
UniProtKB:A0A8M1P6F8
InterPro
1084
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA supt5h-201 (1)
Ensembl
Havana 3868 nt
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-supt5h polyclonal Rabbit
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations
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