FIGURE

FIGURE 10

ID

ZDB-FIG-260720-17

Publication

Perone et al., 2026 - Aip mutation leads to significant alterations in gene expression, altered sensitivity to Ahr ligands, and early lethality in zebrafish

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FIGURE 10

Genes with differential transcript usage (DTU) (Benjamini–Hochberg FDR-adjusted q-value ≤0.05) from the five dpf RNA-seq data. The predicted functional consequence of DTUs with isoform fraction (dIF) ≥ |0.1| is on the x-axis, and the gene expressing each DTU is on the y-axis. These functional consequences correspond to the structure of the transcript with increased abundance in aip^−/− larvae vs. the more abundant transcript in aip^+/+ larvae. Genes with more than one transcript in differential usage are in red. Genes that are also DEGs are denoted by an asterisk, *. 32 genes had DTUs that were predicted to result in functional consequences at the transcript or protein level, with 10 shared between the lines. Each line had 11 unique genes with DTU. Only six of the DTU genes were also DEGs.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	aip^wh86/wh86 aip^wh239/wh239
Observed In:	gene expression
Stage:	Day 5

Phenotype Detail

Acknowledgments

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