FIGURE

Fig. 2

ID

ZDB-FIG-260528-23

Publication

Martinez-Mayer et al., 2026 - Generation of a prop1 knockin zebrafish enables single-cell transcriptomics of early pituitary development

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Fig. 2

Characterization of a prop1 knockout line. (A) prop1 knockouts (−/−) compared to their wild-type (+/+) or heterozygous (+/−) siblings. Growth was evaluated every 15 days, starting from 45 dpf until 90 dpf. (B) prop1−/− zebrafish present reduced length compared to controls. (C) Full body weight comparison between prop1−/− and their wildtype counterparts at 90 dpf. (D) prop1−/− show signs of hypopituitarism (left to right): diffuse pattern and lack of pigmentation on the pelvic fin, poor development of external genital papilla, lack of skin pigmentation, and dispersion of melanophores. Data are represented as mean ± SEM (n = 4, Repeated-measures ANOVA genotype *P < .01 vs genotypes, post hoc Fisher analysis).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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