IMAGE

Fig. 2

ID: ZDB-IMAGE-260528-23
Publication: Martinez-Mayer et al., 2026 - Generation of a prop1 knockin zebrafish enables single-cell transcriptomics of early pituitary development
All Figures: Figures for Martinez-Mayer et al., 2026

Image

Figure Caption

Fig. 2 Characterization of a prop1 knockout line. (A) prop1 knockouts (−/−) compared to their wild-type (+/+) or heterozygous (+/−) siblings. Growth was evaluated every 15 days, starting from 45 dpf until 90 dpf. (B) prop1−/− zebrafish present reduced length compared to controls. (C) Full body weight comparison between prop1−/− and their wildtype counterparts at 90 dpf. (D) prop1−/− show signs of hypopituitarism (left to right): diffuse pattern and lack of pigmentation on the pelvic fin, poor development of external genital papilla, lack of skin pigmentation, and dispersion of melanophores. Data are represented as mean ± SEM (n = 4, Repeated-measures ANOVA genotype *P < .01 vs genotypes, post hoc Fisher analysis).

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Endocrinology