FIGURE

Fig. 1

ID

ZDB-FIG-260322-19

Publication

Solheim et al., 2026 - Early motor deficits, sleep dysfunction and reduction in dopaminergic neurons in a PARK7^-/- zebrafish larval model of Parkinson's disease

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Fig. 1

Larval gross morphology and embryonic spontaneous tail coilings are not altered in PARK7^-/-. (A) Western blot shows expression of DJ-1 at 1, 3 and 5 dpf in total lysates from wild type zebrafish and the lack of DJ-1 in PARK7^-/- zebrafish. Arrow points to DJ-1 band. Pon-S was used as loading control. (B) Images of 5 dpf wild type and PARK7^-/- larvae indicating eye aspect ratio (white, C) and body length (red, D) measurements. (E) Spontaneous coilings of the tail were recorded for 3 min at 28 hpf. T-test of genotypes showed no significance difference (p > 0.05). Graph shows the mean + /- SEM, n = 63–66 embryos per condition, sampled from at least five independent breedings.

Expression Data

Gene:	park7
Fish:	WT park7^{ub2000/ub2000}
Anatomical Term:	whole organism
Stage Range:	Prim-5 to Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	park7^{ub2000/ub2000}
Observed In:	eye whole organism
Stage Range:	Prim-5 to Day 5

Phenotype Detail

Acknowledgments

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