FIGURE

Fig. 1

ID

ZDB-FIG-260210-167

Publication

Gao et al., 2026 - Mutations in VPS18 lead to a neutrophil maturation defect associated with disturbed vesicle homeostasis

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Fig. 1

Mutations in Vps18 cause a maturation defect in neutrophils.

A Representative microscopic images of CTRL, clone 1, clone 2 and VPS18 rescue Hoxb8 cells stained with May-Grünwald-Giemsa during differentiation (day 0–4). Scale bar, 10 µm. B Quantification of promyelocytes, myelocytes, metamyelocytes, band cells, mature neutrophils and dead cells of indicated genotypes in % (100%, all cells) from (A). n = 5 with a minimum of 200 cells per genotype. Mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 compared to CTRL, ^##P < 0.01, ^####P < 0.0001 compared to clone 1. Two-way ANOVA, Tukey’s multiple comparisons test.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

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