FIGURE

Fig. 4.

ID

ZDB-FIG-251230-88

Publication

Mensching et al., 2025 - Cohesin protein Smc3 influences kinocilial structure and function

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Fig. 4.

Smc3 protein depletion does not significantly impact FM1-43FX uptake via mechanotransduction. (A) Maximum projection representative images of first posterior lateral line neuromasts of each injection type following brief FM1-43FX treatment in 6 dpf embryos. (B) Quantification of the average fluorescence intensity normalized to background fluorescence of neuromasts of each injection type. Scale bar: 10.4 µm in the x and y dimensions. Student’s t-test, P=0.3646, SC-KD n=14, Smc3-KD n=11.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	C32 + MO4-smc3
Knockdown Reagent:	MO4-smc3
Observed In:	neuromast hair cell mechanosensitive monoatomic ion channel activity
Stage:	Day 6

Phenotype Detail

Acknowledgments

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