FIGURE

Figure 1

ID

ZDB-FIG-251208-80

Publication

Martínez-Balsalobre et al., 2025 - Telomerase and alternative lengthening of telomeres coexist in the regenerating zebrafish caudal fins

Other Figures

All Figure Page

Back to All Figure Page

Figure 1

Fish with different telomerase genotypes regenerate with different efficiency.

(A) Experimental design of a regeneration assay with a single amputation (black dotted tracing) and growth monitoring (arrowhead and line), at three different ages of life (4, 8, and 11 month old) in tert+/+, tert+/−, and tert−/− zebrafish for 24 days. The caudal peduncle is indicated in a blue dotted line. (B) Caudal fin regeneration slope of 8-month-old zebrafish from the three genotypes. The arrows indicate 100% regeneration of the tail fin. n = 3 experiments with two biological replicates each. Data were mean + s.e.m. (C) Days post amputation to reach 50% of the caudal fin regeneration at three different ages and from the three telomerase genotypes. n = 3 experiments. Each dot represents a biological replicate. Data were mean + standard deviation ***P < 0.001 and ****P < 0.0001 for two-way ANOVA plus Dunnett’s post hoc test. dpa days post amputation. When exact p values are not indicated is because GraphPad Prism software does not show it. Source data are available online for this figure.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ EMBO Rep.