FIGURE

Figure 1.

ID

ZDB-FIG-251128-11

Publication

Zang et al., 2025 - An EAAT2b/SLC1A2b-mediated chloride leak current enables rapid cone photoreceptor signalling

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Figure 1.

Characterization of eaat2b mutant zebrafish. The mutation causes a deletion that results in a premature stop codon, leading to a predicted truncated EAAT2b protein (A,B). Retinal histological sections from adult wild-type (C), adult eaat2b^−/− (D), 5 dpf wild-type (E) and 5 dpf eaat2b^−/− (F) zebrafish show no apparent morphological abnormalities in either larval or adult eyes. Immunofluorescence staining for EAAT2b (green) and Bodipy (magenta) is shown in adult wild-type (G) and eaat2b^−/− (H) retinas. GCL, ganglion cell layer; INL, inner nuclear layer; IPL, inner plexiform layer; OPL, outer plexiform layer; PhR, photoreceptors; TM, transmembrane domain.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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