FIGURE

Figure 2.

ID

ZDB-FIG-251105-31

Publication

Hall et al., 2025 - Comparison of the Differing Impacts of Lowered N-Acetylglucosaminyltransferase-Ia/b Activity on Motor and Sensory Function in Zebrafish

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Figure 2.

Increased levels of oligomannose-type N-glycans in adult mgat1a−/− zebrafish. Lectin blots of tissue homogenates from mgat1a+/+, mgat1a−/− and mgat1a+/− fish, as indicated (A–F). Electrophoresed proteins were probed with GNL (left panels). Protein gels stained with Coomassie blue (CB) (right panels) to demonstrate equal protein loads among the samples. Quantification of the oligomannosylated proteins from swim bladder (SB, n = 3), skin (S, n = 3), heart (H, n = 3), skeletal muscle (SM, n = 3), spinal cord (SC, n = 3), and brain (B, n = 4) (G). Numbers adjacent to the blots denote protein markers (in kDa). Data is mean ± S.E. and compared via Student’s t-test (* p at 0.05).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	mgat1a^{ecu301/ecu301} (AB) mgat1a^ecu301/+ (AB)
Observed In:	brain protein N-acetylglucosaminyltransferase activity heart protein N-acetylglucosaminyltransferase activity integument protein N-acetylglucosaminyltransferase activity skeletal muscle protein N-acetylglucosaminyltransferase activity spinal cord protein N-acetylglucosaminyltransferase activity swim bladder protein N-acetylglucosaminyltransferase activity
Stage:	Adult

Phenotype Detail

Acknowledgments

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