FIGURE

Fig. 4

ID

ZDB-FIG-251023-132

Publication

Malavašič et al., 2025 - Membrane Palmitoylated Protein 7 is Required for Osteogenesis and is Linked with Bone Mineralization and Osteoporosis: The Functional Evaluation of GEFOS GWAS Hit

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Fig. 4

Mineralization and ALPL expression are abolished in MPP7-KO cells. Wild-type (WT) and MPP7-KO HOS cells were cultured in osteogenic differentiation medium and analyzed every 7 days up to day 35. A Representative light microscopy images of differentiating WT and MPP7-KO cells stained with Alizarin Red S to detect calcium deposits (red). Scale bars represent 1 mm. B Relative mRNA expression of alkaline phosphatase (ALPL) as determined by RT-qPCR. C Quantification of Alizarin Red S staining by spectrophotometry. Data represent mean ± SD of three independent biological replicates (N = 3), *P ≤ 0.05; **P ≤ 0.01

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Calcif. Tissue Int.