FIGURE

Fig. 6

ID

ZDB-FIG-251023-134

Publication

Malavašič et al., 2025 - Membrane Palmitoylated Protein 7 is Required for Osteogenesis and is Linked with Bone Mineralization and Osteoporosis: The Functional Evaluation of GEFOS GWAS Hit

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Fig. 6

MPP7 knockout disrupts cell-layer morphology during osteogenic differentiation. Wild-type (WT) and MPP7-KO HOS cells were cultured under osteogenic conditions, and morphological changes in the developing cell layer were assessed. Representative images show: A WT cells at day 14 of differentiation, B WT cells at day 21, C non-differentiated WT cells at day 21, and DMPP7-KO cells at day 21 of differentiation. Arrowheads indicate the margins of circular structures forming within the cell layer, and asterisks denote mineral deposits detected by Alizarin Red S staining. Scale bars represent 1 mm

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Calcif. Tissue Int.