FIGURE

Fig. 2

ID
ZDB-FIG-251008-2
Publication
Han et al., 2025 - The repurposed STAT3 inhibitor pyrimethamine controls mycobacterial infection-induced vascular permeability and mycobacterial burden
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Fig. 2

Inhibition of STAT3 with repurposed small molecules reduces infection-induced vascular permeability. (A) Representative microangiography images of M. marinum-infected zebrafish treated with 50 µM atovaquone or pyrimethamine. (B) Quantification of M. marinum burden in trunk infected zebrafish embryos treated with 50 µM atovaquone or pyrimethamine from 6 to 7 dpi. (C) Quantification of infection-induced vascular permeability in trunk infected zebrafish embryos treated with 50 µM atovaquone or pyrimethamine from 6 to 7 dpi.

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