Fig. 8

Myt1l mutation impacted feeding in a high effort situation. (A) Schematic of the feeding assay timeline. (B) During magazine training, Het mice consumed more pellets during only the inactive phase than WT littermates. (C–D) During dual active training, Het and WT mice consumed a comparable number of pellets (C) and exhibited a similar number of nose pokes (D). (E–F) During FR1 training, Het mice poked into the correct hole at a comparable percent to WT mice (E), resulting in a similar number of pellets consumed between groups (F). (G–H) During resetting PR testing, Het mice consumed more pellets (G) and exhibited a marginal increase in correct hole pokes (H). Sample size for the feeding assay in panel B. Data are represented as means ± SEM with individual points presented as open circles. Repeated measures ANOVA used for statistical comparisons