FIGURE

Fig. 6

ID

ZDB-FIG-250910-15

Publication

Maloney et al., 2025 - A survey of hypothalamic phenotypes identifies molecular and behavioral consequences of MYT1L haploinsufficiency in male and female mice

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Fig. 6

MYT1L haploinsufficiency showed no effect on sexual maturity. (A) Female and male Het mice have similar average adrenal weights compared to WTs. (B–C) Combined ovary weights in female Het mice (B) and combined testes weights in male Het mice (C) were comparable to WTs. (D) Body weights of these mice were also similar between genotypes. Ages (postnatal day) at dissection and weight (Median [Range]): WT male (82 [59–110]), WT Female (87, [62–110], Het male (84, [59–110]), Het female (90, [62–110]). (E–F) WT and Het female and male littermates reached sexual maturity at a similar age (E) and at a similar weight (F). Sample size for gland weights is presented in panel A. Sample size for sexual maturity assessment is presented in panel E. Data are represented as means ± SEM with individual points presented as open circles. ANOVA (A, D–F) and Unpaired t-test (B–C) used for statistical comparisons.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Horm. Behav.