FIGURE

Fig. 12

ID

ZDB-FIG-250821-30

Publication

Bentanachs et al., 2025 - Telmisartan Reverses Hepatic Steatosis via PCK1 Upregulation: A Novel PPAR-independent Mechanism in Experimental Models of MASLD

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Fig. 12

Telmisartan proposed mechanism of action. Blue arrows correspond to the direction of the metabolic flux following telmisartan treatment. Grey and blue sings next to the metabolites indicate the metabolomic analysis results for the HFHFr and Tel groups respectively. 1,3-p-GA: 1,3-phosphoglyceric acid; 2/3-PG: 2/3-phosphoglyceric acid; DHAP: dihydroxyacetone phosphate; F-1-p: fructose 1-phosphate; F-1,6-p: fructose 1,6-diphosphate; F-6-p: fructose 6-phosphate; G-6-p: glucose 6-phosphate; GA3P: glyceraldehyde 3-phosphate; GSH: reduced glutathione; GSSG: oxidized glutathione; OAA: oxalacetate; PCK1: phosphoenolpyruvate carboxykinase 1; PEP: phosphoenolpyruvic acid; PRPP: phosphoribosyl pyrophosphate.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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