FIGURE

Fig. 7

ID

ZDB-FIG-250807-38

Publication

Wang et al., 2025 - EPHA4 signaling dysregulation links abnormal locomotion and the development of idiopathic scoliosis

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Fig. 7

Left-right coordination defects in efnb3b morphants. (A) Fluorescent images showing the distribution of ascending axons of cerebrospinal fluid-contacting neurons (CSF-cNs) marked by Tg(pkd2l1:GAL4,UAS:Kaede) in 2 days post-fertilization (dpf) efnb3b morphants. The red arrows indicate aberrantly extended axons in efnb3b morphants. (B) Fluorescent images showing the dorsal view of 24 hr post-fertilization (hpf) Tg(elavl3:GAL4; UAS:GCaMP) transgenic larvae. (C) The line chart showing the quantification of fluorescence changes of the region of interests (ROIs) in control morphants and efnb3b morphants as indicated in panel B. (D) Superimposed frames of tail oscillations in 5 dpf control and efnb3b morphants. (E) A plot of body curvature angles in panel (D). The positive angle means turning right. Scale bars: 50 μm in panels (A, B).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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