FIGURE

Figure 2

ID

ZDB-FIG-250727-3

Publication

Ouyang et al., 2025 - Salidroside inhibits melanin synthesis and melanoma growth via mTOR and PI3K/Akt pathways

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Figure 2

Salidroside affected melanin in early zebrafish embryos. (A) Survival rate of embryos within 72-h salidroside-treated zebrafish embryos and morphological deformity rates (including pericardial oedema, spine curvature, and tail abnormality) in salidroside-treated (0–72 hpf) zebrafish embryos (n = 80 for each group). (B) Representative images of zebrafish embryos after 48 h of salidroside exposure at different concentrations (0, 0.8,1.6 and 3.2 mM). Scale bar, 500 μm. (C) Effects of salidroside on mRNA expression levels of genes related to melanin synthesis in early zebrafish embryos. ns, no significance, *p < 0.05, **p < 0.01, ***p < 0.005, ****p < 0.001 compared with the control. Results were denoted as mean ± SD of three independent experiments. (D) Expression patterns of oca2 and tyr by whole-mount in situ hybridization in two-day-old zebrafish embryos. Scale bars, 250 μm. SD, standard deviation.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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