FIGURE

Fig. 8

ID

ZDB-FIG-250707-8

Publication

Ramamurthy et al., 2025 - Efficacy of 6-nitrobenzo[d]thiazol-2 Amine Derivative (N3) in Mitigating PTZ-Induced Epileptic Conditions Via Modulation of Inflammatory and Neuroprotective Pathways in-vivo Zebrafish

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Fig. 8

Effect of N3 in PTZ-induced epilepsy-like condition in zebrafish larvae by reducing the calcification and β-amyloid plaques. The graph represents (A) Alizarin red staining in zebrafish larvae (scale 50 μm), (B) Thioflavin S staining in zebrafish larvae (scale 100 μm), (C) Percentage of alizarin red stained region in larvae using Image J software and (D) Percentage of β-amyloid plaques in individual. Experimental groups (n = 15/group) included zebrafish larvae treated with N3 at 50 µM, N3 at 100 µM, PTZ (6 mM), PC - Valproic acid at 100 µM, and control group. Each assay was conducted in triplicate with three independent experiments. Data are expressed as mean ± standard deviation (SD). Statistical significance was determined using one-way ANOVA followed by Dunnett’s multiple comparison test. Significant differences between tested samples and the negative control are indicated by ****p < 0.0001

Expression Data

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Antibody Labeling

Phenotype Data

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Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Neuroimmune Pharmacol.