FIGURE

Fig. 6

ID

ZDB-FIG-250707-6

Publication

Ramamurthy et al., 2025 - Efficacy of 6-nitrobenzo[d]thiazol-2 Amine Derivative (N3) in Mitigating PTZ-Induced Epileptic Conditions Via Modulation of Inflammatory and Neuroprotective Pathways in-vivo Zebrafish

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Fig. 6

Histology analysis of larvae head region using haematoxylin and eosin (H & E) staining in PTZ-induced epilepsy-like condition in zebrafish larvae (scale 50 μm). The graph represents (A) the H&E-stained larvae section, (B) the Percentage of cell damages in the larvae section, (C) H&E scores in the larvae section. Experimental groups (n = 15/group) included zebrafish larvae treated with N3 at 50 µM, N3 at 100 µM, PTZ (6 mM), PC - Valproic acid at 100 µM, and control group. Each assay was conducted in triplicate with three independent experiments. Data are expressed as mean ± standard deviation (SD). Statistical significance was determined using one-way ANOVA followed by Dunnett’s multiple comparison test. Significant differences between tested samples and the negative control are indicated by **p < 0.0021, ****p < 0.0001, and ns - no significance. N-Necrosis, S-Steatosis, D-Degeneration, CL- Cellular infiltration

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Neuroimmune Pharmacol.