Fig. 6
- ID
- ZDB-FIG-250528-24
- Publication
- Kaus-Drobek et al., 2025 - From discovery to potential application: engineering a novel M23 peptidase to combat Listeria monocytogenes
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Safety profile of StM23_CWT. (A) Unchanged morphology of zebrafish larvae at 96 hpf. Left panel shows lateral views of control and zebrafish larvae treated with 1µM StM23_CWT. Bar plot (right panel) demonstrate unchanged body length of zebrafish one of the indicators of unaffected development. Scale bar = 1 mm. (B) The Kaplan-Meier plots show the percentage of G. mellonella larvae surviving challenge with StM23_CWT. (C) The results of the MTT assay on mouse fibroblasts (NIH 3T3) and human keratinocytes (HaCAT) for 1 µM and 5 µM are presented as the percentage of cell viability. Error bar shows SD (n = 3 replicates, 9 wells per replicate). |