FIGURE

Fig. 1

ID

ZDB-FIG-250521-1

Publication

Windster et al., 2024 - Human enteric glia diversity in health and disease: new avenues for the treatment of Hirschsprung disease

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Fig. 1

A single-cell transcriptomic landscape of the pediatric ENS. (A) Schematic of human gut tissue sampling. (B) ENS cells were enriched via CD56+CD90+ in an FACS plot. (C) Uniform manifold approximation and projection visualization showed unsupervised clustering of healthy control ileum and colon ENS cells, indicating the presence of canonical enteric glia 1–2 (EG 1–2) and Schwann-like enteric glia 1–6 (sEG 1–6). (D) Dot plot showing expression of differentially expressed genes across different cell clusters. (E) Heat map showing differentially expressed transcription factors stratified by major classes of captured cells. AUC, area under the curve.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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