FIGURE

Fig. 2

ID

ZDB-FIG-250421-74

Publication

Huybrechts et al., 2025 - Loss of the Ubiquitin-Associated Domain of sqstm1/p62 in Zebrafish Causes a Phenotype Resembling Paget's Disease of Bone

Other Figures

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Fig. 2

Physical characteristics of sqstm1tmΔUBA zebrafish. a Loss of pigmentation on the flanks and profound redness is evident on the lateral view of sqstm1tmΔUBA/tmΔUBA zebrafish at 6 mpf. This discoloration extends from the snout to the operculum and the chest area. The ventral view shows involvement of the pectoral portion of the ventral side (arrow). b, c Standard length and relative weight of zebrafish at 6 and 12 mpf. Statistical testing was performed using Kruskal–Wallis Tests/Mann–Whitney U Tests. Abbreviations: WT, wild type (sqstm1+/+); HET, heterozygous mutant (sqstm1tmΔUBA/+); HOM, homozygous mutant (sqstm1.tmΔUBA/tmΔUBA)

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	sqstm1^{zf4282/zf4282} (AB) sqstm1^zf4282/+ (AB)
Observed In:	whole organism
Stage:	Adult

Phenotype Detail

Acknowledgments

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