FIGURE

Fig. 4

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ZDB-FIG-250414-68

Publication

Karacicek et al., 2025 - The Role of tRNA Fragments on Neurogenesis Alteration by H₂O₂-induced Oxidative Stress

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Fig. 4

Role of tRF-Glu-CTC inhibition on neurogenesis of NSCs. A Expression levels of neurogenesis markers (ßIII-tubulin, MAP2, and GFAP) after transfection of SCR and tRF-Glu-CTC antisense 2′-OMe-RNA (inhibitor) in 50 μM H₂O₂ for 6 h for neurogenesis markers (data are presented as mean ± SD, n = 6, t-test, BIIITUB t-test, C-SCR vs. H₂O₂-SCR p = 0.097 and C-INH vs. H₂O₂-INH p = 0.171, MAP2 t-test, C-SCR vs. H₂O₂-SCR p = 0.067 and C-INH vs. H₂O₂-INH p = 0.054, GFAP t-test, C-SCR vs. H₂O₂-SCR p = 0.090, C-INH vs. H₂O₂-INH, Mann–Whitney test p = 0.180). B Immunofluorescence images of neurogenesis markers (ßIII-tubulin, MAP2, and GFAP) after transfection (images were taken 20 × magnification, Olympus IX61 fluorescent microscope). INH, inhibitor; SCR, scramble

Expression Data

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Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Mol. Neurosci.