Fig 6

ctu1 deficiency reduces the activity of the angpt and notch signaling pathways originated from the endothelial cells in mesoderm.

Bar plot shows overview number (A) and strength (B) in control and ctu1 morphant. (C) Ranking of active signaling pathways in control and ctu1 morphant based on their overall information flow within the inferred cellular networks. Signaling pathways are colored according to condition where they are enriched. (D) The chord plot shows angpt signaling in sending and receiving cells. Nodes are colored by celltypes. The thickness of the line represents the strength of the signal. (E) Dot plots show communication probability of angpt signaling between endothelial cells (senders) and each celltypes (receivers). Blue, low communication probability; red, high communication probability. Size of circle represents the pvalue of cells with communication probability. Chord plots (F) and Dot plots (G) shows notch signaling pathway network.