FIGURE

Fig. 1

ID

ZDB-FIG-250109-16

Publication

Li et al., 2024 - Folic acid mitigates the developmental and neurotoxic effects of bisphenol A in zebrafish by inhibiting the oxidative stress/JNK signaling pathway

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Fig. 1

FA can improve the developmental toxic effects induced by BPA exposure in zebrafish embryos or larvae. (A) FA has the potential to enhance the hatchability of zebrafish embryos exposed to BPA. (B) The survival rate of larvae exposed to BPA can be improved by FA. (C-E) The images depict the control group, as well as larvae exposed to 30 µM of BPA alone or in combination with 50 µM of FA at 120 hpf. (F) The proportion of BPA-induced spinal curvature phenotypes in larvae can be alleviated by FA. (G) The phenotype of body length reduction in larvae induced by BPA exposure can be rescued by FA (n=9). (H) FA can mitigate the decreased heart rate phenotype induced by exposure to BPA in larvae (n=9). The significance levels are denoted as follows: *P<0.05; ** P<0.01; *** P<0.001; and "ns" indicates not significant. The error bars in the figures depict the standard error of the mean.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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