FIGURE

Figure 5

ID

ZDB-FIG-241129-39

Publication

Wu et al., 2024 - Multiple mechanisms of aminoglycoside ototoxicity are distinguished by subcellular localization of action

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Figure 5

Neomycin and G418 differentially accumulate in Rab7+ vesicles. (A) G418-TR (magenta) accumulation in Rab7+ vesicles (green) in neuromast from Tg(myosin6b:EGFP-Rab7a) transgenic line. (A') G418-TR signal is mainly in vesicles. (B) Neo-TR (magenta) accumulation in Rab7+ vesicles (green) in neuromast from Tg(myosin6b:EGFP-Rab7a) transgenic line. (B') Neo-TR signal is found in vesicles and cytoplasm. (C) Ratio of G418-TR and Neo-TR found in Rab7+ vesicles compared to cytoplasm. Shading indicates measurements from three separate experiments. **Unpaired T-test, p < 0.01. Error bars represent Standard Deviation.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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