FIGURE

Figure 6.

ID

ZDB-FIG-241127-28

Publication

Roux et al., 2024 - Transcriptional profiling of zebrafish intestines identifies macrophages as host cells for human norovirus infection

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Figure 6.

Single-cell analysis reveals inhibition of cytoplasmic translation and enhanced phagocytosis in HuNoV-infected macrophages. (a) A volcano plot shows the DEGs in HuNoV-infected vs. uninfected bystander macrophages within the HuNoV-infected zebrafish host. A vertical dotted line marks a log₂(fold change) value of 0.5, while the horizontal dotted line marks a benjamini-Hochberg q-value of 0.05. Dot plot showing the pathways obtained via a ClueGO hypergeometric enrichment pathway analysis of (b) downregulated and (c) upregulated DEGs using the gene ontology - biological process database. HuNoV = human norovirus, DEGs = differentially expressed genes.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Gut Microbes