FIGURE

Fig. 6

ID

ZDB-FIG-241119-93

Publication

Yin et al., 2024 - Lactate secreted by glycolytic conjunctival melanoma cells attracts and polarizes macrophages to drive angiogenesis in zebrafish xenografts

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Fig. 6

Inhibition of glycolysis attenuates macrophage-dependent angiogenesis of CoM cells. a Schematic diagram of 2DG treatment in cancer cells prior to their xenografting in zebrafish larvae. b Representative images of the angiogenesis response of embryos xenografted with CoM lines treated with and without 2DG treatment. c Quantification of the angiogenesis response in these conditions. d Quantification of the pro-angiogenic factors VEGF-A (vegfaa) and TGF-β (tgfb1a) in engrafted zebrafish

Expression Data

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Antibody Labeling

Phenotype Data

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Acknowledgments

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