FIGURE

Fig. 7

ID

ZDB-FIG-241015-17

Publication

Ling et al., 2024 - Establishment of a Diamond-Blackfan anemia like model in zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Fig. 7

ESA responses of epoaszy8. (A) Schematic diagram of the ESA treatment. The embryos were exposed to rHuEPO at 1.5-dpf and fixed at 4-dpf from epoaheterozygous intercross. (B) Anemia indicated by decreased αe1+ cells in epoaszy8 larvae, and the erythrocytes expansion by rHuEPO. Images of WT and epoaszy8 embryos treated with sodium chloride salin control and rHuEPO (C) Statistical significance was determined using a two-sample Student's t-test, n > 10, mean ± SD, *p < .05, **p < .01, ***p < .001. Scale bars: 50 μm. (D) Predisone responses of epoaszy8, statistical significance was determined using a two-sample Student's t-test, n ≥ 7, mean ± SD, ns: no significance.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	epoa^szy8/szy8
Condition:	chemical treatment by environment: Erythropoietin
Observed In:	nucleate erythrocyte
Stage:	Day 4

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dev. Dyn.