FIGURE

Figure 3

ID

ZDB-FIG-240930-141

Publication

Trengove et al., 2024 - Zebrafish Suppressor of Cytokine Signaling 4b (Socs4b) Is Dispensable for Development but May Regulate Epidermal Growth Factor Receptor Signaling

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Figure 3

Investigation of the socs4bΔ18 mutants. Light microscopy of homozygous socs4b WT (+/+; (A)) and socs4bΔ18 (Δ/Δ; (B)) embryos at 2 dpf. Homozygous socs4b WT (+/+; (C,E,G,I,K)) and socs4bΔ18 (Δ/Δ; (D,F,H,J,L)) embryos subjected to WISH at the indicated times with specific probes for ins ((C), n = 35; (D), n = 33), isl1a ((E), n = 42; (F), n = 38), lyz ((G), n = 27; (H), n = 30), and rag1 ((I), n = 40; (J), n = 37) viewed by light microscopy or staining with Mitotracker Red (mito) ((K), n = 23; (L), n = 25) and viewed by fluorescence microscopy. The number of embryos analyzed with each stain is shown. Scale bars = 1 mm.

Expression Data

Genes:	ins isl1a lyz rag1
Fish:	WT socs9^{zf4236/zf4236}
Anatomical Terms:	central nervous system leukocyte pancreatic B cell pro-T cell
Stage Range:	Prim-15 to Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	socs9^{zf4236/zf4236}
Observed In:	neuromast whole organism
Stage Range:	Long-pec to Day 5

Phenotype Detail

Acknowledgments

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