FIGURE

Fig. 7

ID

ZDB-FIG-240916-71

Publication

Aky�rek et al., 2024 - The Accordion Zebrafish tq206 Mutant in the Assessment of a Novel Pharmaceutical Approach to Brody Myopathy

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Fig. 7

Representative Western blot showing the expression level analysis of WT, S766F mutant SERCA1 proteins after incubation with proteasome inhibitor MG132 and CFTR correctors at different concentrations. HeLa cells transfected with WT and S766F SERCA1 cDNAs were treated with the proteasome inhibitor MG132 (10 �M) or its vehicle DMSO (0.1%) and S766F mutants were also exposed to different concentrations of C17 and C4 CFTR correctors. An equal quantity of protein from total cell lysates was separated by SDS-PAGE and subjected to immunoblot analysis with antibodies specific to SERCA1 and 42 kDa beta-actin, used as loading control.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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