FIGURE
Fig. 6
- ID
- ZDB-FIG-240828-43
- Publication
- Caetano da Silva et al., 2024 - Functional analysis of ESRP1/2 gene variants and CTNND1 isoforms in orofacial cleft pathogenesis
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Fig. 6
Over-expression of ctnnd1 rescues esrp1−/−, esrp2−/− epithelial phenotypes.A Image representing how wildtype, intermediate and cleft ANC, pectoral fins and otoliths were sorted. B Representative table with the number of total fish injected and rescued by the ctnnd1 mRNA injection with GFP mRNA injection as control. Scoring of ANC phenotype (%) (C), fin phenotype (%) (D) and the otolith phenotype (%) (E) in the injected esrp1−/−; esrp2+/− inter-cross larvae confirmed by genotyping, showing 20–22% rescue of ANC, fin and otolith phenotypes in the esrp1−/−; esrp2−/− double homozygous larvae. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Observed In: | |
| Stage: | Day 4 |
Phenotype Detail
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