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FIGURE 6

ID

ZDB-FIG-240813-8

Publication

Zhang et al., 2024 - CM082 suppresses hypoxia-induced retinal neovascularization in larval zebrafish

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FIGURE 6

CM082 partially rescued visual motor response (VMR) deficiency induced by hypoxia. (A) Time frame of VMR. (B, C) Motor activity in response to light-on and light-off in larval zebrafish which were exposed to EM, DMSO, 0.5 or 1 μM CM082 in both normoxia and hypoxia conditions. The activities of normoxia groups are higher than hypoxia groups. (D, E) Motor activity in response to light-on and light-off in larval zebrafish which were exposed to EM, DMSO, 0.5 or 1 μM CM082 under hypoxia. (F, G) The activity of light onset and light offset in eight groups. There was no significant difference among the normoxic groups. However, the activity in hypoxia was significantly reduced and it was partially rescued by CM082. n = 12 in each group. *p < 0.05; **p < 0.01; ***p < 0.001. Data represent the mean ± SEM.

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Acknowledgments

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