FIGURE
Fig. 4 Supplemental 1
- ID
- ZDB-FIG-240801-18
- Publication
- Nakayama et al., 2021 - A zebrafish embryo screen utilizing gastrulation identifies the HTR2C inhibitor pizotifen as a suppressor of EMT-mediated metastasis
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Fig. 4 Supplemental 1
HTR2C promoted EMT-mediated metastatic dissemination of poorly metastatic human cancer cells in a zebrafish xenotransplantation model. (A) Quantification analyses of western blotting bands in Figure 4C. The analyses were performed by ImageJ. Signal strength of bands of E-cadherin, EpCAM, N-cadherin, vimentin, ZEB1, and HTR2C was normalized by that of GAPDH. (B) Representative images of dissemination patterns of MCF7 cells expressing either the control vector (top left, middle left, bottom left) or HTR2C (top right, middle right, bottom right) in a zebrafish xenotransplantation model. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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