FIGURE

Fig. 5 Supplemental 1

ID

ZDB-FIG-240729-44

Publication

Weiss et al., 2024 - A syngeneic spontaneous zebrafish model of tp53-deficient, EGFR^vIII, and PI3KCA^H1047R-driven glioblastoma reveals inhibitory roles for inflammation during tumor initiation and relapse in vivo

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Fig. 5 Supplemental 1

Quantitative real-time PCR analysis of control, primary tumor, and engrafted whole brains. (A) Quantitative real-time PCR analysis of neural stem cell (NSC) genes and inflammation genes in non-tumor control brains, pooled p53EPS-burdened brains, and pooled brains engrafted with p53EPS tumor cells at 20 days post fertilization (dpf). *p<0.01 compared to non-tumor control whole brain tissue, Student’s t-test. (B) Quantitative real-time PCR analysis of NSC genes and inflammation genes at 20 dpf in primary transplanted (1T) p53EPS-burdened brains injected with vehicle control liposomes (1T p53EPS) and Clodrosomes at 2 dpf. At least five tumor-burdened brains were pooled for each cohort and expression was normalized to mScarlet mRNA expression to account for differences in tumor size. *p<0.01 compared to 1T p53EPS, Student’s t-test.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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