FIGURE

Fig. 4

ID

ZDB-FIG-240702-22

Publication

Caporale et al., 2019 - Transcriptional Enhancers in the FOXP2 Locus Underwent Accelerated Evolution in the Human Lineage

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Fig. 4

Detailed foxP2 expression analysis in zebrafish. (A) Bright field microphotographs of developing wild-type zebrafish. (B) foxP2 WMISH at 24 (B1), 48 (B2), and 72 hpf (B3) showing the endogenous expression in zebrafish. Scale bar: 500 ?m. (C) Bright field image of a wild-type zebrafish at 72 hpf where red lines indicate the approximate location of the coronal cryosections shown below. Serial cryostat sections showing chromogenic ISH (D1, E1, F1, G1), fluorescent ISH (D2, E2, F2, G2) and IHC (D3, E3, F3, G3) to detect endogenous foxP2. Confocal microphotographs showing merged images of ISH (E4a) and IHC (E4b) realized on the same cryostat section. Double-positive cells in the tectum are indicated by arrowheads in E4c. Scale bar (E4): 100 ?m, Scale bar (E4c): 10 ?m. cb, cerebellum; di, diencephalon; hb, hindbrain; mhb, midbrain?hindbrain boundary; not, notochord; ov, otic vesicle; sc, spinal cord; tec, tectum; tel, telencephalon; tal, thalamus (tal); y, yolk sac.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Mol Bio Evol