FIGURE

Fig. 1

ID

ZDB-FIG-240628-42

Publication

Mashayekhi et al., 2024 - The RNA binding protein IGF2BP2/IMP2 alters the cargo of cancer cell-derived extracellular vesicles supporting tumor-associated macrophages

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Fig. 1

Characterization of HCT116 parental and KO cell-derived EVs isolated via the TFF system. A, B Representative NTA size distribution profiles of isolated EVs. C, D NanoSight quantification of EV preparations' size (C) and concentration (D) are shown as mean � SD, n = 3 individual EV isolation, triplicates). E Cryo-TEM images of EVs, scale bar: 500 nm. F Abundance of 25 vesicle markers in WT and KO cells and EVs. Values are shown as log2 signal intensity of three independent preparations. G Cellular internalization of EVs into primary macrophages (1:10,000 cell:EV). Cells were incubated for 24 h with WT and KO EVs labeled with CFSE. Magnification, 63x, scale bar: 10 �m

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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